Complicated and Fragile Another reason that such small concentrations can affect you is that they operate inside of tiny cells that are complicated and fragile. And that makes it a matter both of scale and potency. The cells in your body are like a well-run city maintained with carefully balanced mechanisms that produce energy, get […]
Author Archive | Lewis Perdue
Serious flaws found in Lancet study “debunking myth” of healthy moderate alcohol consumption
By Lewis Perdue Co-Principal Investigator Stealth Syndromes Human Study Co-founder, Stealth Syndromes Project Chairman, Center for Research on Environmental Chemicals in Humans NOTE: You may right-click all images to view a larger version The recent Lancet study that found no cardio-protective benefits of moderate alcohol consumption is marred by substantial problems which raise serious concerns […]
The Mendelian Randomization by Millwood et al.: Observations and Expressions of Concern
By Lewis Perdue Co-Principal Investigator Stealth Syndromes Human Study Co-founder, Stealth Syndromes Project Chairman, Center for Research on Environmental Chemicals in Humans The recent population study of adults in China that found no cardio-protective benefits of moderate alcohol consumption should be re-examined in the context of methodological and confounding factors not addressed in the published […]
Two criteria for the evolutionary selection of ALDH2*2 other than as a protection against alcohol disorder
Adaptive Genetic Variation and Population Differences Author links open overlay panelChao-QiangLai https://doi.org/10.1016/B978-0-12-398397-8.00018-6 “It is unlikely that the high frequency of these risk alleles was under recent selection by alcoholism. “Goldman and Enoch93 proposed two possible types of selection. First, mycotoxins (aflatoxins, in particular), which can cause hepatic disease and cancer, are commonly present in moldy […]
Paleogenetics looks at the origins of the ability to metabolize alcohol
Humans have been consuming ethyl alcohol — ethanol — for millions of years. Indeed, the ability to consume alcohol may have shaped primate evolution. Humans have this ability because, in addition to obvious beverage sources, alcohol is present in many common foods such as bread and other bakery products, fruit and fruit juices (Gorgus, et, […]
Sources for Under-Reporting of Alcohol Consumption
Sources, Under-Reporting Underreporting in alcohol surveys: whose drinking is underestimated? Drinking pattern is more strongly associated with under-reporting of alcohol consumption than socio-demographic factors: evidence from a mixed-methods study Estimating under- and over-reporting of drinking in national surveys of alcohol consumption: Identification of consistent biases across four English-speaking countries How is alcohol consumption affected if […]
All moderate alcohol consumption studies are “all over the charts”
All moderate alcohol consumption studies are “all over the charts” because they are epidemiological and plagued by confounding factors no matter how hard investigators work to control for those. Epidemiology is a correlative method that cannot conclude causation. This is true even with newer statistical techniques such as Mendelian Randomization.For an extended examination of the […]
Press Coverage Examples
News Release: Moderate alcohol consumption does not protect against stroke CNBC: Major study debunks myth that moderate drinking can be healthy Reuters: Major study debunks myth that moderate drinking can be healthy Click this Google Search link for more
Random humans: Thank a Moravian pea farmer.
Each human is randomly unique because: Genes reside on chromosomes. Humans have 23 pairs of chromosomes. Each member of a pair of chromosomes are not identical. Egg and sperm cells under go a division (meiosis) that leaves each of them only one half of the chromosomes. The fertilization process is a random scramble with no […]
Sources, Under-Reporting of Alcohol Consumption
Sources, Under-Reporting Underreporting in alcohol surveys: whose drinking is underestimated? Drinking pattern is more strongly associated with under-reporting of alcohol consumption than socio-demographic factors: evidence from a mixed-methods study Estimating under- and over-reporting of drinking in national surveys of alcohol consumption: Identification of consistent biases across four English-speaking countries How is alcohol consumption affected if […]